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Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous system diseases characterized by the degeneration of lower motor neurons. They share a number of additional pathological, cellular, and genetic parallels suggesting that mechanistic and clinical insights into on...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Tosolini, Andrew P., Sleigh, James N.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725447/
https://ncbi.nlm.nih.gov/pubmed/29270111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00405
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