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Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous system diseases characterized by the degeneration of lower motor neurons. They share a number of additional pathological, cellular, and genetic parallels suggesting that mechanistic and clinical insights into on...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Tosolini, Andrew P., Sleigh, James N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725447/
https://ncbi.nlm.nih.gov/pubmed/29270111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00405
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