A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I

Lecithin:cholesterol acyltransferase (LCAT) plays a key role in reverse cholesterol transport by transferring an acyl group from phosphatidylcholine to cholesterol, promoting the maturation of high-density lipoproteins (HDL) from discoidal to spherical particles. LCAT is activated through an unknown...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Manthei, Kelly A., Ahn, Joomi, Glukhova, Alisa, Yuan, Wenmin, Larkin, Christopher, Manett, Taylor D., Chang, Louise, Shayman, James A., Axley, Milton J., Schwendeman, Anna, Tesmer, John J. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724016/
https://ncbi.nlm.nih.gov/pubmed/29030428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802736
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi