Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles

Lecithin:cholesterol acyltransferase (LCAT) catalyzes a critical step of reverse cholesterol transport by esterifying cholesterol in high density lipoprotein (HDL) particles. LCAT is activated by apolipoprotein A-I (ApoA-I), which forms a double belt around HDL, however the manner in which LCAT enga...

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Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Manthei, Kelly A., Patra, Dhabaleswar, Wilson, Christopher J., Fawaz, Maria V., Piersimoni, Lolita, Shenkar, Jenny Capua, Yuan, Wenmin, Andrews, Philip C., Engen, John R., Schwendeman, Anna, Ohi, Melanie D., Tesmer, John J. G.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962161/
https://ncbi.nlm.nih.gov/pubmed/31942029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0749-z
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