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Accurate assembly of transcripts through phase-preserving graph decomposition
We introduce Scallop, an accurate reference-based transcript assembler that improves reconstruction of multi-exon and lowly expressed transcripts. Scallop preserves long-range phasing paths extracted from reads, while producing a parsimonious set of transcripts and minimizing coverage deviation. On...
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| Published in: | Nat Biotechnol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722698/ https://ncbi.nlm.nih.gov/pubmed/29131147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4020 |
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