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Pre-Clinical Evaluation of a Themosensitive Gel Containing Epothilone B and mTOR/Hsp90 Targeted Agents in an Ovarian Tumor Model

Despite clinical remission of epithelial ovarian cancer (EOC) after surgical resection and first-line chemotherapy, about 60% of patients will re-develop peritoneal metastasis and about 50% will relapse with chemoresistant disease. Clinical studies suggest that intra-peritoneal (i.p.) chemotherapy e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Control Release
Hauptverfasser: Shin, Dae Hwan, Kwon, Glen S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722673/
https://ncbi.nlm.nih.gov/pubmed/29056443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.10.022
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