iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA

VISA (also known as MAVS, IPS-1 and Cardif) is an essential adaptor protein in innate immune response to RNA virus. The protein level of VISA is delicately regulated before and after viral infection to ensure the optimal activation and timely termination of innate antiviral response. It has been rep...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Luo, Wei-Wei, Li, Shu, Li, Chen, Zheng, Zhou-Qin, Cao, Pan, Tong, Zhen, Lian, Huan, Wang, Su-Yun, Shu, Hong-Bing, Wang, Yan-Yi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722342/
https://ncbi.nlm.nih.gov/pubmed/29155878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006693
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