iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice

iRhom1 and iRhom2 are inactive homologues of rhomboid intramembrane serine proteases lacking essential catalytic residues, which are necessary for the maturation of TNFα-converting enzyme (TACE). In addition, iRhoms regulate epidermal growth factor family secretion. The functional significance of iR...

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Udgivet i:PLoS One
Main Authors: Leilei, Yang, Bing, Liu, Yang, Li, Shaoxia, Wang, Yuan, Xu, Dongping, Wang, Huahu, Ye, Shichen, Shang, Guangzhou, Zhang, Ruiyun, Peng, Lin, Zeng, Wenlong, Li
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278852/
https://ncbi.nlm.nih.gov/pubmed/25546423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115114
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