iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA

VISA (also known as MAVS, IPS-1 and Cardif) is an essential adaptor protein in innate immune response to RNA virus. The protein level of VISA is delicately regulated before and after viral infection to ensure the optimal activation and timely termination of innate antiviral response. It has been rep...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Luo, Wei-Wei, Li, Shu, Li, Chen, Zheng, Zhou-Qin, Cao, Pan, Tong, Zhen, Lian, Huan, Wang, Su-Yun, Shu, Hong-Bing, Wang, Yan-Yi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722342/
https://ncbi.nlm.nih.gov/pubmed/29155878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006693
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