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Synthesis of Diarylated 4-Pyridylmethyl Ethers via Palladium-Catalyzed Cross-Coupling Reactions
The direct arylation of weakly acidic sp(3)–hybridized C–H bonds via deprotonated cross–coupling processes (DCCP) is a challenge. Herein, a Pd(NIXANTPHOS)-based catalyst for the mono arylation of 4-pyridylmethyl 2-aryl ethers to generate diarylated 4-pyridyl methyl ethers is introduced. Furthermore,...
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| Publicado no: | Adv Synth Catal |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722243/ https://ncbi.nlm.nih.gov/pubmed/29230153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201700380 |
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