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Palladium-Catalyzed Benzylic Arylation of Pyridylmethyl Silyl Ethers: One-Pot Synthesis of Aryl(pyridyl)methanols
An efficient palladium-catalyzed direct arylation of pyridylmethyl silyl ethers with aryl bromides is described. A Pd(OAc)(2)/NIXANTPHOS-based catalyst provides aryl(pyridyl)-methyl alcohol derivatives in good to excellent yields (33 examples, 57–100% yield). This protocol is compatible with differe...
Tallennettuna:
| Julkaisussa: | Org Lett |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887141/ https://ncbi.nlm.nih.gov/pubmed/27004592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00450 |
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