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Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling

Epithelial–mesenchymal transition (EMT) plays key roles during embryonic development, wound healing and cancer metastasis. Cells in a partial EMT or hybrid epithelial/mesenchymal (E/M) phenotype exhibit collective cell migration, forming clusters of circulating tumour cells—the primary drivers of me...

詳細記述

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書誌詳細
出版年:J R Soc Interface
主要な著者: Bocci, Federico, Jolly, Mohit K., Tripathi, Satyendra C., Aguilar, Mitzi, Hanash, Samir M., Levine, Herbert, Onuchic, José N.
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721160/
https://ncbi.nlm.nih.gov/pubmed/29187638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0512
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