NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype

The epithelial-mesenchymal transition (EMT) is a key process implicated in cancer metastasis and therapy resistance. Recent studies have emphasized that cells can undergo partial EMT to attain a hybrid epithelial/mesenchymal (E/M) phenotype – a cornerstone of tumour aggressiveness and poor prognosis...

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Detalhes bibliográficos
Publicado no:Integr Biol (Camb)
Main Authors: Bocci, Federico, Tripathi, Satyendra C, Vilchez Mercedes, Samuel A, George, Jason T, Casabar, Julian P, Wong, Pak Kin, Hanash, Samir M, Levine, Herbert, Onuchic, José N, Jolly, Mohit Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686740/
https://ncbi.nlm.nih.gov/pubmed/31329868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intbio/zyz021
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