Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype

Metastasis can involve repeated cycles of epithelial-to-mesenchymal transition (EMT) and its reverse mesenchymal-to-epithelial transition. Cells can also undergo partial transitions to attain a hybrid epithelial/mesenchymal (E/M) phenotype that allows the migration of adhering cells to form a cluste...

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Detalles Bibliográficos
Publicado en:J R Soc Interface
Autores principales: Boareto, Marcelo, Jolly, Mohit Kumar, Goldman, Aaron, Pietilä, Mika, Mani, Sendurai A., Sengupta, Shiladitya, Ben-Jacob, Eshel, Levine, Herbert, Onuchic, Jose’ N.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2016
Materias:
Life Sciences–Physics interface
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892257/
https://ncbi.nlm.nih.gov/pubmed/27170649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.1106
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