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Jagged mediates differences in normal and tumor angiogenesis by affecting tip-stalk fate decision
Angiogenesis is critical during development, wound repair, and cancer progression. During angiogenesis, some endothelial cells adopt a tip phenotype to lead the formation of new branching vessels; the trailing stalk cells proliferate to develop the vessel. Notch and VEGF signaling mediate the select...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517227/ https://ncbi.nlm.nih.gov/pubmed/26153421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511814112 |
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