Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization

B cell activating factor receptor (BAFFR)(-/-) mice have a profound reduction in mature B cells, but unlike μMT mice, they have normal numbers of newly formed, immature B cells. Using a West Nile virus (WNV) challenge model that requires antibodies (Abs) for protection, we found that unlike wild-typ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Giordano, Daniela, Draves, Kevin E., Young, Lucy B., Roe, Kelsey, Bryan, Marianne A., Dresch, Christiane, Richner, Justin M., Diamond, Michael S., Gale, Michael, Clark, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720816/
https://ncbi.nlm.nih.gov/pubmed/29176765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006743
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados