Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses

Mitochondrial antiviral signaling protein (MAVS) is a critical innate immune signaling protein that directs the actions of the RIG-I-like receptor (RLR) signaling pathway of RNA virus recognition and initiation of anti-viral immunity against West Nile virus (WNV). In the absence of MAVS, mice die mo...

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Udgivet i:PLoS One
Main Authors: Roe, Kelsey, Giordano, Daniela, Young, Lucy B., Draves, Kevin E., Holder, Ursula, Suthar, Mehul S., Gale, Michael, Clark, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594639/
https://ncbi.nlm.nih.gov/pubmed/31242236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218928
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