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Splenic macrophages are required for protective innate immunity against West Nile virus

Although the spleen is a major site for West Nile virus (WNV) replication and spread, relatively little is known about which innate cells in the spleen replicate WNV, control viral dissemination, and/or prime innate and adaptive immune responses. Here we tested if splenic macrophages (MΦs) were nece...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bryan, Marianne A., Giordano, Daniela, Draves, Kevin E., Green, Richard, Gale, Michael, Clark, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800658/
https://ncbi.nlm.nih.gov/pubmed/29408905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191690
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