Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization

B cell activating factor receptor (BAFFR)(-/-) mice have a profound reduction in mature B cells, but unlike μMT mice, they have normal numbers of newly formed, immature B cells. Using a West Nile virus (WNV) challenge model that requires antibodies (Abs) for protection, we found that unlike wild-typ...

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Vydáno v:PLoS Pathog
Hlavní autoři: Giordano, Daniela, Draves, Kevin E., Young, Lucy B., Roe, Kelsey, Bryan, Marianne A., Dresch, Christiane, Richner, Justin M., Diamond, Michael S., Gale, Michael, Clark, Edward A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720816/
https://ncbi.nlm.nih.gov/pubmed/29176765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006743
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