Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau

Microtubule-associated proteins regulate microtubule dynamics, bundle actin filaments, and cross-link actin filaments with microtubules. In addition, aberrant interaction of the microtubule-associated protein Tau with filamentous actin is connected to synaptic impairment in Alzheimer’s disease. Here...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Cabrales Fontela, Yunior, Kadavath, Harindranath, Biernat, Jacek, Riedel, Dietmar, Mandelkow, Eckhard, Zweckstetter, Markus
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719408/
https://ncbi.nlm.nih.gov/pubmed/29215007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02230-8
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