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STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis. In these applications, target cells are extremely rare and fragile in peripheral circulation, which makes the genetic analysis very...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Vander Plaetsen, Ann-Sophie, Deleye, Lieselot, Cornelis, Senne, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Deforce, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719346/
https://ncbi.nlm.nih.gov/pubmed/29215049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17525-5
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