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Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing
Starting from only a few cells, current whole genome amplification (WGA) methods provide enough DNA to perform massively parallel sequencing (MPS). Unfortunately, all current WGA methods introduce representation bias which limits detection of copy number aberrations (CNAs) smaller than 3 Mb. A recen...
Shranjeno v:
izdano v: | Sci Rep |
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Main Authors: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Nature Publishing Group
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992833/ https://ncbi.nlm.nih.gov/pubmed/27546482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31825 |
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