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TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPol
Sequencing of a single-cell genome requires DNA amplification, a process prone to introducing bias and errors into the amplified genome. Here we introduce a novel multiple displacement amplification (MDA) method based on the unique DNA primase features of Thermus thermophilus (Tth) PrimPol. TthPrimP...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5141293/ https://ncbi.nlm.nih.gov/pubmed/27897270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13296 |
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