The active site of TthPolX is adapted to prevent 8-oxo-dGTP misincorporation

Full genome sequencing of bacterial genomes has revealed the presence of numerous genes encoding family X DNA polymerases. These enzymes play a variety of biological roles and, accordingly, display often striking functional differences. Here we report that the PolX from the heat-stable organism Ther...

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Bibliografiske detaljer
Main Authors: Garrido, Patricia, Mejia, Edison, Garcia-Diaz, Miguel, Blanco, Luis, Picher, Angel J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874185/
https://ncbi.nlm.nih.gov/pubmed/24084083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt870
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