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Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair intermediate

Incorporation of mismatched nucleotides during DNA replication or repair leads to transition or transversion mutations and is considered as a predominant source of base substitution mutagenesis in cancer cells. Watson-Crick like dG:dT base pairing is considered to be an important source of genome in...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Çağlayan, Melike, Wilson, Samuel H.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181931/
https://ncbi.nlm.nih.gov/pubmed/30310068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06700-5
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