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Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair intermediate
Incorporation of mismatched nucleotides during DNA replication or repair leads to transition or transversion mutations and is considered as a predominant source of base substitution mutagenesis in cancer cells. Watson-Crick like dG:dT base pairing is considered to be an important source of genome in...
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| Publicado no: | Nat Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6181931/ https://ncbi.nlm.nih.gov/pubmed/30310068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06700-5 |
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