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STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis. In these applications, target cells are extremely rare and fragile in peripheral circulation, which makes the genetic analysis very...

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書目詳細資料
發表在:Sci Rep
Main Authors: Vander Plaetsen, Ann-Sophie, Deleye, Lieselot, Cornelis, Senne, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Deforce, Dieter
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719346/
https://ncbi.nlm.nih.gov/pubmed/29215049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17525-5
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