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STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis. In these applications, target cells are extremely rare and fragile in peripheral circulation, which makes the genetic analysis very...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Vander Plaetsen, Ann-Sophie, Deleye, Lieselot, Cornelis, Senne, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Deforce, Dieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719346/
https://ncbi.nlm.nih.gov/pubmed/29215049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17525-5
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