Multiplex STR amplification sensitivity in a silicon microchip

The demand for solutions to perform forensic DNA profiling outside of centralized laboratories is increasing. We here demonstrate highly sensitive STR amplification using a silicon micro-PCR (µPCR) chip. Exploiting industry-standard semiconductor manufacturing processes, a device was fabricated that...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Cornelis, Senne, Fauvart, Maarten, Gansemans, Yannick, Vander Plaetsen, Ann-Sophie, Colle, Frederik, Wiederkehr, Rodrigo S., Deforce, Dieter, Stakenborg, Tim, Van Nieuwerburgh, Filip
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026139/
https://ncbi.nlm.nih.gov/pubmed/29959383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28229-9
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