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Performance of four modern whole genome amplification methods for copy number variant detection in single cells

Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of cells. Unfortunately, current WGA methods introduce representation bias that limits the detection of small CNVs. New WGA methods have been introduced that...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Deleye, Lieselot, Tilleman, Laurentijn, Vander Plaetsen, Ann-Sophie, Cornelis, Senne, Deforce, Dieter, Van Nieuwerburgh, Filip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469777/
https://ncbi.nlm.nih.gov/pubmed/28611458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03711-y
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