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Performance of four modern whole genome amplification methods for copy number variant detection in single cells

Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of cells. Unfortunately, current WGA methods introduce representation bias that limits the detection of small CNVs. New WGA methods have been introduced that...

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Publicado en:Sci Rep
Autores principales: Deleye, Lieselot, Tilleman, Laurentijn, Vander Plaetsen, Ann-Sophie, Cornelis, Senne, Deforce, Dieter, Van Nieuwerburgh, Filip
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469777/
https://ncbi.nlm.nih.gov/pubmed/28611458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03711-y
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