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Sortase Transpeptidases: Structural Biology and Catalytic Mechanism

Gram-positive bacteria use sortase cysteine transpeptidase enzymes to covalently attach proteins to their cell wall and to assemble pili. In pathogenic bacteria sortases are potential drug targets, as many of the proteins that they display on the microbial surface play key roles in the infection pro...

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Bibliografiske detaljer
Udgivet i:Adv Protein Chem Struct Biol
Main Authors: Jacobitz, Alex W., Kattke, Michele D., Wereszczynski, Jeff, Clubb, Robert T.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718342/
https://ncbi.nlm.nih.gov/pubmed/28683919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2017.04.008
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