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Sortase Transpeptidases: Structural Biology and Catalytic Mechanism

Gram-positive bacteria use sortase cysteine transpeptidase enzymes to covalently attach proteins to their cell wall and to assemble pili. In pathogenic bacteria sortases are potential drug targets, as many of the proteins that they display on the microbial surface play key roles in the infection pro...

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Podrobná bibliografie
Vydáno v:Adv Protein Chem Struct Biol
Hlavní autoři: Jacobitz, Alex W., Kattke, Michele D., Wereszczynski, Jeff, Clubb, Robert T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718342/
https://ncbi.nlm.nih.gov/pubmed/28683919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2017.04.008
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