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Sortase Transpeptidases: Structural Biology and Catalytic Mechanism

Gram-positive bacteria use sortase cysteine transpeptidase enzymes to covalently attach proteins to their cell wall and to assemble pili. In pathogenic bacteria sortases are potential drug targets, as many of the proteins that they display on the microbial surface play key roles in the infection pro...

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Библиографические подробности
Опубликовано в: :Adv Protein Chem Struct Biol
Главные авторы: Jacobitz, Alex W., Kattke, Michele D., Wereszczynski, Jeff, Clubb, Robert T.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718342/
https://ncbi.nlm.nih.gov/pubmed/28683919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2017.04.008
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