Identification of coexistence of BRAF V600E mutation and EZH2 gain specifically in melanoma as a promising target for combination therapy

BACKGROUND: Coexistence of enhancer of zeste homolog 2 (EZH2) and BRAF gene aberrations has been described in many cancer types. In this study, we aim to explore the coexistence status of BRAF V600E mutation and the copy number variation of EZH2 and explore the potential of this combination as a the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Yu, Huan, Ma, Meng, Yan, Junya, Xu, Longwen, Yu, Jiayi, Dai, Jie, Xu, Tianxiao, Tang, Huan, Wu, Xiaowen, Li, Siming, Lian, Bin, Mao, Lili, Chi, Zhihong, Cui, Chuanliang, Guo, Jun, Kong, Yan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716227/
https://ncbi.nlm.nih.gov/pubmed/29202777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1344-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker