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Increased AURKA Gene Copy Number Correlates with Poor Prognosis and Predicts the Efficacy of High-dose Interferon Therapy in Acral Melanoma

Background: AURKA kinase is an essential serine/threonine kinase for mitosis and chromosome stability. The aberrant amplification and overexpression of AURKA are commonly observed in various types of cancer, including cutaneous melanoma. However, the status and the clinical significance of AURKA cop...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Yan, Junya, Yu, Jiayi, Wu, Xiaowen, Xu, Tianxiao, Yu, Huan, Dai, Jie, Ma, Meng, Tang, Huan, Xu, Longwen, Chi, Zhihong, Si, Lu, Sheng, Xinan, Cui, Chuanliang, Kong, Yan, Guo, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907675/
https://ncbi.nlm.nih.gov/pubmed/29675108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.24013
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