Anti-GD2/4-1BB chimeric antigen receptor T cell therapy for the treatment of Chinese melanoma patients

BACKGROUND: Chimeric antigen receptor (CAR)-engineered T cells have demonstrated promising clinical efficacy in patients with B cell lymphoma. However, the application of CAR-T cell therapy in the treatment of other solid tumors has been limited. We incorporated 4-1BB into the anti-GD2 CAR-T cells t...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Yu, Jiayi, Wu, Xiaowen, Yan, Junya, Yu, Huan, Xu, Longwen, Chi, Zhihong, Sheng, Xinan, Si, Lu, Cui, Chuanliang, Dai, Jie, Ma, Meng, Xu, Tianxiao, Kong, Yan, Guo, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751546/
https://ncbi.nlm.nih.gov/pubmed/29298689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0548-2
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