Mutations in BRAF codons 594 and 596 predict good prognosis in melanoma

B-Raf proto-oncogene serine/threonine kinase (BRAF) V600E is the most common kinase-activating mutation and is associated with poor prognosis in melanoma. However, the clinical significance of kinase-impairing mutations remains unclear. The present study aimed to analyze kinase-impairing mutations i...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Wu, Xiaowen, Yan, Junya, Dai, Jie, Ma, Meng, Tang, Huan, Yu, Jiayi, Xu, Tianxiao, Yu, Huan, Si, Lu, Chi, Zhihong, Sheng, Xinan, Cui, Chuanliang, Kong, Yan, Guo, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587919/
https://ncbi.nlm.nih.gov/pubmed/28927118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6608
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