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Anti-aggregant tau mutant promotes neurogenesis

BACKGROUND: The microtubule-associated protein Tau plays a role in neurodegeneration as well as neurogenesis. Previous work has shown that the expression of the pro-aggregant mutant Tau repeat domain causes strong aggregation and pronounced neuronal loss in the hippocampus whereas the anti-aggregant...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Joseph, Maria, Anglada-Huguet, Marta, Paesler, Katharina, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715613/
https://ncbi.nlm.nih.gov/pubmed/29202785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0230-8
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