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Basis and Statistical Design of the Passive HIV-1 Antibody Mediated Prevention (AMP) Test-of-Concept Efficacy Trials

BACKGROUND: Anti-HIV-1 broadly neutralizing antibodies (bnAbs) have been developed as potential agents for prevention of HIV-1 infection. The HIV Vaccine Trials Network and the HIV Prevention Trials Network are conducting the Antibody Mediated Prevention (AMP) trials to assess whether, and how, intr...

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Foilsithe in:Stat Commun Infect Dis
Main Authors: Gilbert, Peter B., Juraska, Michal, deCamp, Allan C., Karuna, Shelly, Edupuganti, Srilatha, Mgodi, Nyaradzo, Donnell, Deborah J., Bentley, Carter, Sista, Nirupama, Andrew, Philip, Isaacs, Abby, Huang, Yunda, Zhang, Lily, Capparelli, Edmund, Kochar, Nidhi, Wang, Jing, Eshleman, Susan H., Mayer, Kenneth H., Magaret, Craig A., Hural, John, Kublin, James G., Gray, Glenda, Montefiori, David C., Gomez, Margarita M., Burns, David N., McElrath, Julie, Ledgerwood, Julie, Graham, Barney S., Mascola, John R., Cohen, Myron, Corey, Lawrence
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714515/
https://ncbi.nlm.nih.gov/pubmed/29218117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/scid-2016-0001
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