Basis and Statistical Design of the Passive HIV-1 Antibody Mediated Prevention (AMP) Test-of-Concept Efficacy Trials

BACKGROUND: Anti-HIV-1 broadly neutralizing antibodies (bnAbs) have been developed as potential agents for prevention of HIV-1 infection. The HIV Vaccine Trials Network and the HIV Prevention Trials Network are conducting the Antibody Mediated Prevention (AMP) trials to assess whether, and how, intr...

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Publicado no:Stat Commun Infect Dis
Main Authors: Gilbert, Peter B., Juraska, Michal, deCamp, Allan C., Karuna, Shelly, Edupuganti, Srilatha, Mgodi, Nyaradzo, Donnell, Deborah J., Bentley, Carter, Sista, Nirupama, Andrew, Philip, Isaacs, Abby, Huang, Yunda, Zhang, Lily, Capparelli, Edmund, Kochar, Nidhi, Wang, Jing, Eshleman, Susan H., Mayer, Kenneth H., Magaret, Craig A., Hural, John, Kublin, James G., Gray, Glenda, Montefiori, David C., Gomez, Margarita M., Burns, David N., McElrath, Julie, Ledgerwood, Julie, Graham, Barney S., Mascola, John R., Cohen, Myron, Corey, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714515/
https://ncbi.nlm.nih.gov/pubmed/29218117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/scid-2016-0001
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