Use of Placebos in Phase 1 Preventive HIV Vaccine Clinical Trials

Phase 1 preventive HIV vaccine trials are often designed as randomized, double-blind studies with the inclusion of placebo recipients. Careful consideration is needed to determine when the inclusion of placebo recipients is highly advantageous and when it is optional for achieving the study objectiv...

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Publicat a:Vaccine
Autors principals: Huang, Yunda, Karuna, Shelly T, Janes, Holly, Frahm, Nicole, Nason, Martha, Edlefsen, Paul T, Kublin, James G, Corey, Lawrence, McElrath, M. Juliana, Gilbert, Peter B
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554766/
https://ncbi.nlm.nih.gov/pubmed/25454855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.10.017
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