Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition

BACKGROUND: Whether a broadly neutralizing antibody (bnAb) can be used to prevent human immunodeficiency virus type 1 (HIV-1) acquisition is unclear. METHODS: We enrolled at-risk cisgender men and transgender persons in the Americas and Europe in the HVTN 704/HPTN 085 trial and at-risk women in sub-...

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Publicado en:N Engl J Med
Main Authors: Corey, L., Gilbert, P.B., Juraska, M., Montefiori, D.C., Morris, L., Karuna, S.T., Edupuganti, S., Mgodi, N.M., deCamp, A.C., Rudnicki, E., Huang, Y., Gonzales, P., Cabello, R., Orrell, C., Lama, J.R., Laher, F., Lazarus, E.M., Sanchez, J., Frank, I., Hinojosa, J., Sobieszczyk, M.E., Marshall, K.E., Mukwekwerere, P.G., Makhema, J., Baden, L.R., Mullins, J.I., Williamson, C., Hural, J., McElrath, M.J., Bentley, C., Takuva, S., Lorenzo, M.M. Gomez, Burns, D.N., Espy, N., Randhawa, A.K., Kochar, N., Piwowar-Manning, E., Donnell, D.J., Sista, N., Andrew, P., Kublin, J.G., Gray, G., Ledgerwood, J.E., Mascola, J.R., Cohen, M.S.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189692/
https://ncbi.nlm.nih.gov/pubmed/33730454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2031738
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