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Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV
Bryostatin 1 is an exceedingly scarce marine-derived natural product that is in clinical development directed at HIV/AIDS eradication, cancer immunotherapy, and the treatment of Alzheimer’s disease. Despite this unique portfolio of indications, its availability has been limited and variable, thus im...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714505/ https://ncbi.nlm.nih.gov/pubmed/29026042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan7969 |
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