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Measuring deaminated nucleotide surveillance enzyme ITPA activity with an ATP-releasing nucleotide chimera

Nucleotide quality surveillance enzymes play important roles in human health, by detecting damaged molecules in the nucleotide pool and deactivating them before they are incorporated into chromosomal DNA or adversely affect metabolism. In particular, deamination of adenine moiety in (deoxy)nucleosid...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ji, Debin, Stepchenkova, Elena I., Cui, Jian, Menezes, Miriam R., Pavlov, Youri I., Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714213/
https://ncbi.nlm.nih.gov/pubmed/29036687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx774
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