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Polymerase-amplified release of ATP (POLARA) for detecting single nucleotide variants in RNA and DNA
The identification of single nucleotide polymorphisms (SNP) is increasingly important for diagnosis and treatment of disease. Here we studied the potential use of ATP-releasing nucleotides (ARNs) for identifying SNPs in DNA and RNA targets. Synthesized as derivatives of the four canonical deoxynucle...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429602/ https://ncbi.nlm.nih.gov/pubmed/30996911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03901a |
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