In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys()

We have developed a selective indole antagonist (230) targeting the OXE receptor for the potent eosinophil chemoattractant 5-oxo-ETE (5-oxo-6,8,11,14-eicosatetraenoic acid), that may be useful for the treatment of eosinophilic diseases such as asthma. In previous studies we identified ω2-oxidation o...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Biochem Pharmacol
Autors principals: Chourey, Shishir, Ye, Qiuji, Reddy, Chintam Nagendra, Cossette, Chantal, Gravel, Sylvie, Zeller, Matthias, Slobodchikova, Irina, Vuckovic, Dajana, Rokach, Joshua, Powell, William S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710753/
https://ncbi.nlm.nih.gov/pubmed/28476332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.031
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars