Nalaganje...
Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys
BACKGROUND AND PURPOSE: The 5‐lipoxygenase product 5‐oxo‐6E,8Z,11Z,14Z‐eicosatetraenoic acid (5‐oxo‐ETE), acting through the OXE receptor, is a potent eosinophil chemoattractant that may be an important proinflammatory mediator in eosinophilic diseases such as asthma. We previously identified a seri...
Shranjeno v:
| izdano v: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2020
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989946/ https://ncbi.nlm.nih.gov/pubmed/31655025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14874 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|