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Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid

The 5-lipoxygenase (5-LO) product 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE), which is a potent chemoattractant for myeloid cells, is known to promote the survival of prostate cancer cells. In the present study, we found that PC3 prostate cancer cells and cell lines derived from breast (MCF7)...

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Detalhes bibliográficos
Main Authors: Grant, Gail E., Rubino, Stephen, Gravel, Sylvie, Wang, Xiaoping, Patel, Pranav, Rokach, Joshua, Powell, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146358/
https://ncbi.nlm.nih.gov/pubmed/21393477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr044
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