Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine–Induced Hand-Foot Syndrome: A Randomized Clinical Trial

IMPORTANCE: Hand-foot syndrome (HFS) is a common adverse effect of capecitabine treatment. OBJECTIVE: To compare the incidence and time to onset of grade 2 or greater HFS in patients receiving pyridoxine vs placebo and to identify biomarkers predictive of HFS. DESIGN, SETTING, AND PARTICIPANTS: This...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JAMA Oncol
Päätekijät: Yap, Yoon-Sim, Kwok, Li-Lian, Syn, Nicholas, Chay, Wen Yee, Chia, John Whay Kuang, Tham, Chee Kian, Wong, Nan Soon, Lo, Soo Kien, Dent, Rebecca Alexandra, Tan, Sili, Mok, Zuan Yu, Koh, King Xin, Toh, Han Chong, Koo, Wen Hsin, Loh, Marie, Ng, Raymond Chee Hui, Choo, Su Pin, Soong, Richie Chuan Teck
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Medical Association 2017
Aiheet:
Original Investigation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710192/
https://ncbi.nlm.nih.gov/pubmed/28715540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.1269
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