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Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine–Induced Hand-Foot Syndrome: A Randomized Clinical Trial

IMPORTANCE: Hand-foot syndrome (HFS) is a common adverse effect of capecitabine treatment. OBJECTIVE: To compare the incidence and time to onset of grade 2 or greater HFS in patients receiving pyridoxine vs placebo and to identify biomarkers predictive of HFS. DESIGN, SETTING, AND PARTICIPANTS: This...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:JAMA Oncol
Main Authors: Yap, Yoon-Sim, Kwok, Li-Lian, Syn, Nicholas, Chay, Wen Yee, Chia, John Whay Kuang, Tham, Chee Kian, Wong, Nan Soon, Lo, Soo Kien, Dent, Rebecca Alexandra, Tan, Sili, Mok, Zuan Yu, Koh, King Xin, Toh, Han Chong, Koo, Wen Hsin, Loh, Marie, Ng, Raymond Chee Hui, Choo, Su Pin, Soong, Richie Chuan Teck
פורמט: Artigo
שפה:Inglês
יצא לאור: American Medical Association 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710192/
https://ncbi.nlm.nih.gov/pubmed/28715540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.1269
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