Candidate mechanisms for capecitabine-related hand–foot syndrome

AIMS: The oral fluoropyrimidine prodrug capecitabine is widely used in oncology. Capecitabine was designed to generate 5FU via the thymidine phosphorylase (TP) enzyme, preferentially expressed in tumoral tissues. Hand–foot syndrome (HFS) is a limiting toxicity of capecitabine. A pilot study on healt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Milano, Gérard, Etienne-Grimaldi, Marie-Christine, Mari, Mireille, Lassalle, Sandra, Formento, Jean-Louis, Francoual, Mireille, Lacour, Jean-Philippe, Hofman, Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2008
Aiheet:
Drug Safety
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485249/
https://ncbi.nlm.nih.gov/pubmed/18341672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03159.x
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