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Candidate mechanisms for capecitabine-related hand–foot syndrome
AIMS: The oral fluoropyrimidine prodrug capecitabine is widely used in oncology. Capecitabine was designed to generate 5FU via the thymidine phosphorylase (TP) enzyme, preferentially expressed in tumoral tissues. Hand–foot syndrome (HFS) is a limiting toxicity of capecitabine. A pilot study on healt...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2485249/ https://ncbi.nlm.nih.gov/pubmed/18341672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03159.x |
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