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CRISPR/Cas9-based safe-harbor gene editing in rhesus iPSCs
NHP iPSCs provide a unique opportunity to test safety and efficacy of iPSC-derived therapies in clinically relevant NHP models. To monitor these cells in vivo, there is a need for safe and efficient labeling methods. Gene insertion into genomic safe harbors (GSHs) supports reliable transgene express...
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| Pubblicato in: | Curr Protoc Stem Cell Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709051/ https://ncbi.nlm.nih.gov/pubmed/29140568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpsc.37 |
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